Ongoing Projects

Delayed Treatment in Vascular Surgery

This study aims to illuminate practice patterns and impact of delayed treatment in urgent or emergent vascular conditions (e.g. symptomatic carotid artery stenosis or ruptured aortic aneurysm) on outcomes.

Questions: Maarit Venermo

International Variations in Peripheral Arterial Disease (PAD) Treatment

This study aims to collect population-based data (primary registry data, hospital episode statistics, health insurance claims data) on invasive revascularizations and amputations of the lower limb for all stages of chronic peripheral arterial disease (PAD) and to compare the distribution of patient´s age and gender, the indication and urgency for treatment, the distribution of performed revascularizations among these patients, and the short-term survival.

Questions: ch.behrendt@uke.de and birgitta.sigvant@liv.se

Global Amputation Study (GAS)

In a recently published Vascunet report regarding international variations in amputation practice among 12 European and Australasian countries, large geographical differences in major amputation rates and outcomes were observed.  Several possible explanations such as differences in disease burden and vascular maintenance were discussed by the authors but due to the limited validity of involved study data these attempts to explain observations remained merely speculative. However, various hypotheses were generated and the need for reflection and further research became quite evident. This follow-up project aims to involve all available primary registry data, hospital episode statistics, national statistical data, and health insurance claims data from participating countries worldwide that is suitable to obtain an in-depth insight into global amputation practice. It further aims to illuminate the complex interaction of influencing factors, practice patterns, and outcomes in corresponding populations.

Questions: ch.behrendt@uke.de and Martin Björck

ICVR: Prospective AAA Project (IPAP)

Two projects evaluating AAA device performance will be included in IPAP, both of which aim to enroll consecutive patients for two years:

1. Infrarenal AAA Repair: For this study, both endovascular aortic repair (EVAR) and open repair will be evaluated. The focus of the study will be on device performance and comparative effectiveness between various EVAR devices and open AAA. For EVAR, aortic neck length >= 10 mm will be required, and for Open, a clamp below the renal arteries.
2. Juxtarenal Aortic Repair: Similar to the infrarenal EVAR study, this study evaluates endovascular and open repair of juxtarenal aortic aneurysms. All endovascular techniques/devices including fenestrated EVAR, EVAS and parallel stent techniques (i.e. chimney, snorkel, periscope stents) will be evaluated in aneurysms that include the renals but not superior mesenteric arteries. Neck length will be < 10 mm for EVAR and for Open, a clamp above at least one renal artery.

The IPAP projects are being led by Adam Beck and Kevin Mani. Participating registries include VQI, Swedvasc, NORKAR, GermanVasc, HUSvasc, Hungarian Vascular Registry, Italian Vascular and Endovascular Registry, and Karbase.

Questions: Kevin Mani, Adam W. Beck

ICVR: International Variations in Vascular Surgery (InVASC)

The main focus of the three retrospective InVASC projects is to compare treatment type (open vs. interventional) and patient selection (symptoms, urgency, patient demographics) between and within countries.  The analyses will highlight differences in patient or procedure type selection that might lead to better understanding and reduced variation, and help identify future targets for outcome analysis. The three procedure types of interest are:

1.    EVAR vs. Open AAA Repair (Questions: K. Mani) (Excel Sheet: Data_collection_AAA)
2.    Carotid Endarterectomy vs. Stenting (Questions: M. Venermo)
3.    Infrainguinal Bypass vs. Intervention (Questions: C.-A. Behrendt)

Questions: Kevin Mani, Adam W. Beck, Maarit Venermo